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JaCVAMの研究活動 2026年

2026年

誌上発表（原著論文）

  • Ishigamori R, Ohno A, Fukuhara K, Hasegawa S, Totsuka Y, Genotoxicity assessment of mesoporous silica and graphene oxide in GDL1 cells. PGenes Environ, 2026;48:2. https://doi.org/10.1186/s41021-025-00350-y
  • Tsuchitani T, Midorikawa R, Kasuya A, Noguchi A, Yamamoto K, Nishimura T, Kaji H, Hori T, Tomi M: MCT1-mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell-derived barrier model. J Physiol, 0.0; 2026:1-19. doi.org/10.1113/JP289595
  • Ambe K, Kinoshita K, Tokunaga J, Satake R , Murasaki W, Tohkin M, Yamada T, Ashikaga T: ExSERA: The explainable machine learning model for skin sensitization risk assessment. Regul Toxicol Pharmacol, 2026;169:106100. doi: 10.1016/j.yrtph.2026.106100
  • Nakagawa S, Nukada Y, Saito K, Hisaki T, Sekine S, Tamura A , Ono A, Kuwagata M, Hirota M, Toyoda A, Hatao M, Takahashi Y, Ashikaga T, Yamada T: A Case Study for Utilization of Next Generation Risk Assessment (NGRA) for the Approval of Quasi-Drugs:Predicting the Repeated Dose Toxicity of p-Alkylphenols with Read-Across, Jpn. Cosmet. Sci. Soc, 2026;50(1) :1-12. doi: 10.1016/j.yrtph.2026.106100

誌上発表（総説）

単行本

学会発表・セミナー発表

  • Ashikaga T, Yamada T, Iwasa H, Hatano K, Nakamura N, Kinoshita K, Tokunaga J, Satake R, Murasaki W, Ambe K: Skin sensitization risk assessment using a machine learning model that considers aggregate exposure to cosmetic products. SOT 65th Annual Meeting (2026.3.23, San Diego, CA, USA)
  • Satake R, Tokunaga J, Kinoshita K, Iwasa H, Hatano K, Nakamura N, Arakawa H, Yamada T, Ashikaga T, Ambe K: Next Generation Risk Assessment Case Study: A Quantitative Machine Learning Approach for Skin Sensitization in Oxidative Hair Dyes. SOT 65th Annual Meeting (2026.3.23, San Diego, CA, USA)
  • Toda S, Mizoguchi I, Katahira Y, Yamaguchi N, Horio E, Miyakawa S, Igarashi M, Qu N, Kuroda E, Ashikaga T, Yoshimoto T: Development of human alveolar macrophage model cell lines for the assessment of immunotoxicity of nanoparticles. SOT 65th Annual Meeting (2026.3.23, San Diego, CA, USA)
  • Pellevoisin C, Kojima H, Hoffmann S, Ashikaga T, Landry T, Romero C, Guntur K, Klausner M, Stadnicki J, Gehrke H, Mills-Goodlet R, Panousi N, Johnson VJ, Narita K, Tachibana S, Kojima K, Armento A: Me-Too Validation of the Epi2SensA Method Using EpiDerm Model for Skin Sensitization Testing Under OECD TG442D. SOT 65th Annual Meeting (2026.3.23, San Diego, CA, USA)
  • 山本耕平, 緑川凜, 土谷聡耀, 野口幸希, 堀武志, 梶弘和, 登美斉俊:ヒト胎盤バリアモデルにおけるプロピオン酸双方向輸送：MCT4ではなくMCT1による促進. 日本薬学会第146年会 (2026.3.27, 大阪)
  • 堀武志:ヒト胎盤模倣システムを用いた生殖発達毒性試験法の開発とその国際標準化に向けた取り組み. 日本薬学会第146年会 (2026.3.28, 大阪)
  • 福原潔, 大野彰子: 医療機器におけるナノマテリアルNETs誘導を介した遺伝毒性への新たな視点. 日本薬学会第146年会 (2026.3.28, 大阪)
  • Jiang B, Hori T, Nashimoto Y, Kaji H: A novel device for fabricating artificial blood vessels, 2026 MRS Spring Meeting & Exhibit（2026.4.27, Hawaii, USA）
  • 山口大河, 堀武志, 金光佳世子, Shaji Maneesha, 梨本裕司, 梶弘和: 葉酸のヒト胎盤細胞への影響とヒト胎盤バリアモデルを用いた透過性評価, 化学とマイクロ・ナノシステム学会第53回研究会（2026.5.15, 東京）
  • Yoshida Y, Iriyama T, Ariyoshi Y, Shibuya M, Ariyoshi Y, Yano E, Suzuki K, Hori T, Kaji H, Kumasawa K, Hirota Y: Chimeric VEGF-E/PIGF Protein Selectively Activating VEGFR-2 as a Novel Therapeutic Strategy for Preeclampsia, 第78回日本産科婦人科学会学術講演会（2026.5.15, 札幌）
  • Hori T, Kojima M, Jiang B, Arima T, Kaji H, Tomi M, Ashikaga T: Stem cell-derived human placental models for assessing placental toxicity and transplacental transfer, 2026 MPS World Summit（2026.5.27, Washington D.C, USA）

発表資料